4-Methylumbelliferone

CAS: 90-33-5

Ref. 3D-M-5421

Product Information

• Name: 4-Methylumbelliferone
• Synonyms: 7-Hydroxy-4-methylcoumarin, Hymecromone, 4-Methyl-7-hydroxycoumarin, 4-Mu, 7-Hydroxy-4-methycoumarin, 7-Hydroxy-4-methyl-2-chromenone, 7-Hydroxy-4-methyl-2-oxo-3-chromene, 7-Hydroxy-4-methyl-2H-1-benzopyran-2-one, 7-Hydroxy-4-methyl-2H-chomen-2-one, 7-Hydroxy-4-methyl-2H-chromen-2-on, 7-Hydroxy-4-methyl-2H-chromen-2-one, 7-Hydroxy-4-methylbenzopyran-2-one, 7-Hydroxyl-4-methylcoumarine, Benzopyran(2H-1)-2-One, 7-Hydroxy-4-Methyl-, Bilcolic, Bilicante, Biliton H, Cantabilin, Cantabiline, Cholestil, Cholonerton, Cholspasmin, Coumarin 4, Coumarin 456, Coumarin, 7-hydroxy-4-methyl-, Cumarote C, Eurogale, Himecol, Himecromona, Hymecromon, Imecromone, Lm 94, Medilla, Mendiaxon, Nsc 19026, Nsc 9408, Odeston, Omega 127, Pilot 447, Umbelliferone, 4-methyl-, β-Methylumbelliferone

Description

4-Methylumbelliferone is a coumarin derivative that inhibits the activity of enzymes such as p-nitrophenyl phosphate oxidase and aminopeptidase. It is used in vitro to study oxidative injury, which plays a role in the pathogenesis of inflammatory diseases, including primary sclerosing cholangitis and bone marrow transplantation. 4-Methylumbelliferone has been shown to induce apoptosis by increasing reactive oxygen species levels and activating toll-like receptor 4 (TLR4). It also has inhibitory effects on osteosarcoma cell proliferation in vitro.

• Brand: Biosynth

Chemical properties

• Molecular weight: 176.17 g/mol
• Formula: C₁₀H₈O₃