Auranofin

CAS: 34031-32-8

Ref. 3D-MA05382

Product Information

• Name: Auranofin
• Synonyms: (S)-Triphenylphosphine gold(I) 2,3,4,6-tetra-O-acetyl-b-D-thioglucopyranoside1-Thio-b-D-glucopyranosatotriethylphosphine gold-2,3,4 ,6-tetraacetate3,4,5-Triacetyloxy-6-(acetyloxymethyl) oxane-2-thiolate triethylphosphanium, (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate, 3,4,5-Triacetoxy-6-(Acetoxymethyl)Tetrahydropyran-2-Thiolate, Aktil, Auranofina, Auranofine, Crisinor, Crisofin, Gold Salt, Gold(+1) Cation, Gold, (1-thio-β-<span class="text-smallcaps">D</span>-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate, Gold, (1-thio-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-, Gold, (1-thio-β-D-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate, Gold, (1-thio-β-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-, Gold, [1-(thio-κS)-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-, Gold, [1-(thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-, Nsc 321521, Phosphine, Triethyl-, Gold(1+) Salt (1:1), Ridaura, Ridauran, Skf 39162, Skf 39162D, Triethylphosphonium, [(Tetra-O-acetyl-β-<span class="text-smallcaps">D</span>-glucopyranosyl)thio](triethylphosphine)gold, [(Tetra-O-acetyl-β-D-glucopyranosyl)thio](triethylphosphine)gold, [1-(Thio-κS)-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold, β-<span class="text-smallcaps">D</span>-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex

Description

Auranofin is a chrysotherapeutic agent which inhibits histamine release from human basophils. Auranofin is gold-containing salt extensively used in the treatment of rheumatoid arthritis. Auranofin has antimicrobial properties and inhibits the growth of Clostridium difficile more effectively than vancomycin and metronidazole. According to in vitro studies carried out in 2020, auranofin inhibits the replication of coronavirus SARS-CoV-2 and reduces inflammation in human cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 678.49 g/mol
• Formula: C₂₀H₃₄AuO₉PS
• Color/Form: White Off-White Powder