2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-a-D-glucopyranose

CAS: 7784-54-5

Ref. 3D-MA07519

Product Information

• Name: 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-a-D-glucopyranose
• Synonyms: 1,2,3,4,6-Penta-O-acetyl-a-D-glucosaminea-D-Glucosamine pentaacetate2-(Acetylamino)-2-deoxy-a-D-glucopyranose 1,3,4,6-tetraacetate, 1,3,4,6-Tetra-O-acetyl-2-acetamido-2-deoxy-α-<span class="text-smallcaps">D</span>-glucopyranose, 1,3,4,6-tetra-O-acetyl-2-(acetylamino)-2-deoxy-alpha-D-glucopyranose, 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-<span class="text-smallcaps">D</span>-glucopyranose, 2-Acetamido-2-deoxy-1,3,4,6-tetra-O-acetyl-α-<span class="text-smallcaps">D</span>-glucopyranose, 2-Acetamido-2-deoxy-alpha-D-glucose 1,3,4,6-tetraacetate, 2-Acetamido-2-deoxy-α-<span class="text-smallcaps">D</span>-glucopyranose 1,3,4,6-tetraacetate, 3-Acetamido-6-(acetoxymethyl)tetrahydro-2H-pyran-2,4,5-triyl triacetate, Glucopyranose, 2-acetamido-2-deoxy-, 1,3,4,6-tetraacetate, α-<span class="text-smallcaps">D</span>-, NSC 231931, α-<span class="text-smallcaps">D</span>-Glucopyranose, 2-(acetylamino)-2-deoxy-, 1,3,4,6-tetraacetate

Description

2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-a-D-glucopyranose (2AAT) is a synthetic nucleoside that binds to the same sequence of n-acetylgalactosamine in the cell wall of Gram positive bacteria. It was found to be effective against bacterial strains that produce beta lactamase enzymes. 2AAT has been shown to inhibit the growth of Gram positive bacteria and is able to penetrate tissues. It also prevents bacterial DNA gyrase and topoisomerase IV from binding with their respective substrates. 2AAT is made up of four parts: two ribose molecules, one deoxyribose molecule and one acetamido group. This last part is what makes it bind to the bacterial cell wall and inhibits protein synthesis by preventing mRNA from being translated into proteins.

• Brand: Biosynth

Chemical properties

• Molecular weight: 389.36 g/mol
• Formula: C₁₆H₂₃NO₁₀
• Purity: Min. 98 Area-%
• Color/Form: White Powder