5-Azepan-1-yl-5-deoxy-1,2-isopropylidene-a-D-xylofuranose

CAS: 175229-82-0

Ref. 3D-MA08086

Product Information

• Name: 5-Azepan-1-yl-5-deoxy-1,2-isopropylidene-a-D-xylofuranose

Description

5-Azepan-1-yl-5-deoxy-1,2-isopropylidene-a-(D)-xylofuranose (ADXF) is a synthetic glycoside that was synthesized in order to explore the potential of ADXF as a drug candidate. ADXF has shown promising antiinflammatory and anticancer activities. The synthesis of ADXF starts with the protection of the hydroxyl group at the anomeric center with acetate and then the glycosylation with azepane and 5-deoxy-1,2 isopropylidene erythronolide B. This synthesis also includes fluorination and methylation steps, which are necessary for modifying the sugar structure.

• Brand: Biosynth

Chemical properties

• Molecular weight: 271.35 g/mol
• Formula: C₁₄H₂₅NO₄
• Purity: Min. 95%
• Color/Form: Brown solid.
• InChI: InChI=1S/C14H25NO4/c1-14(2)18-12-11(16)10(17-13(12)19-14)9-15-7-5-3-4-6-8-15/h10-13,16H,3-9H2,1-2H3/t10-,11-,12?,13-/m1/s1
• InChI key: InChIKey=ARLIKICZPKLEDW-ZHRBOBAGSA-N
• SMILES: CC1(C)OC2[C@H](O[C@H](CN3CCCCCC3)[C@H]2O)O1