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2-Amino-2-deoxy-glucitol

CAS:

Ref. 3D-MA137341

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2-Amino-2-deoxy-glucitol
Biosynth

Product Information

Name:2-Amino-2-deoxy-glucitol
Brand:Biosynth
Description:2-Amino-2-deoxy-glucitol is a kinetic inhibitor of the enzyme glycogen phosphorylase, which catalyzes the rate-limiting step in glycogenolysis. It binds to the enzyme and blocks access to the active site by an amide group, thus inhibiting the phosphorylation of glucose residues. This prevents the breakdown of glycogen and leads to increased levels of blood sugar. 2-Amino-2-deoxy-glucitol is used as a treatment for pertussis (whooping cough) and as an adjunct therapy during insulin shock therapy for diabetic ketoacidosis. The drug has also been shown to bind to histidine residues on the enzyme and inhibit its activity.
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Chemical properties

Molecular weight:181.19 g/mol
Formula:C6H15NO5
Purity:Min. 95%
InChI:InChI=1S/C6H15NO5/c7-3(1-8)5(11)6(12)4(10)2-9/h3-6,8-12H,1-2,7H2
InChI key:InChIKey=FQORWEQXRQVPBZ-UHFFFAOYSA-N
SMILES:NC(CO)C(O)C(O)C(O)CO

Technical inquiry about: 2-Amino-2-deoxy-glucitol

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