Allo-3a-tetrahydro cortisol 21-O-b-D-glucuronide

CAS: 131061-62-6

Ref. 3D-MA16588

Product Information

• Name: Allo-3a-tetrahydro cortisol 21-O-b-D-glucuronide
• Synonyms: (3a,5a,11b)-3,11,17-Trihydroxy-20-oxopregnan-21-yl b-D-glucopyranosiduronic acidallo-tetrahydrocortisol 21-glucuronide
• Brand: Biosynth
• Description: Allo-3a-tetrahydro cortisol 21-O-b-D-glucuronide (A4C21) is a complex carbohydrate with a high degree of modification. The A4C21 is synthesized by the glycosylation and methylation of 3,5,6,7,8,9,10,11-hexahydrodehydrocortisol 21-O-b-D-glucuronide. The synthesis starts with the formation of an acetal between the two hydroxyl groups on one side of the steroid nucleus and two chloroform molecules in order to protect the reactant from further reactions. The reaction product is then subjected to a ketalization reaction with thioglycolic acid to yield an alpha/beta unsaturated ketone which is then reacted with ethylene diamine to produce an amide linkage. This amide linkage is then cleaved to yield an aldol condensation product

Chemical properties

• Molecular weight: 542.62 g/mol
• Formula: C₂₇H₄₂O₁₁
• Purity: Min. 95%