Product Information
Dezapelisib is a potent, selective small molecule activator of the human epidermal growth factor receptor 2 (HER2) receptor. It is an antibody-like small molecule that binds to the extracellular domain of the HER2 receptor and activates its signaling pathway. Dezapelisib has been shown to inhibit tumor growth in several different xenograft models, including mouse models of breast cancer and ovarian cancer, as well as in a mouse model of lung cancer. In preclinical studies, dezapelisib has also demonstrated activity against other tumor types including colon cancer and pancreatic cancer. As such, dezapelisib may be useful for treating patients with cancers that have HER2 overexpression or amplification.
Chemical properties
Technical inquiry about: 3D-MAC44025 Dezapelisib
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