Mambalgin-1

Ref. 3D-MAM-3778-PI

Product Information

• Name: Mambalgin-1
• Synonyms: H-Leu-Lys-Cys-Tyr-Gln-His-Gly-Lys-Val-Val-Thr-Cys-His-Arg-Asp-Met-Lys-Phe-Cys-Tyr-His-Asn-Thr-Gly-Met-Pro-Phe-Arg-Asn-Leu-Lys-Leu-Il e-Leu-Gln-Gly-Cys-Ser-Ser-Ser-Cys-Ser-Glu-Thr-Glu-Asn-Asn-Lys-Cys-Cys-Ser-Thr-Asp-Arg-Cys-Asn-Lys-OH
• Brand: Biosynth
• Description: Mambalgin-1 is a natural product with an unknown pharmacophore. It has been shown to inhibit cancer cells in vitro and in vivo by suppressing the activation of suppressor genes, which are genes that regulate cell proliferation. Mambalgin-1 may also be effective against other diseases such as Parkinson's disease, Alzheimer's disease, and Huntington's disease. Mambalgin-1 is synthesized from a solid-phase synthesis of a cyclic peptide that contains two acidic amino acids. This synthetic compound binds to the extracellular region of synaptic vesicles and inhibits the release of neurotransmitters. The mechanism of action is not yet known, but it is thought that this compound may inhibit calcium channels or potassium channels in the presynaptic membrane.

Chemical properties

• Molecular weight: 6,554.61 g/mol
• Formula: C₂₇₂H₄₂₉N₈₅O₈₄S₁₀
• Purity: Min. 95%