2-Chloro-2-deoxy-D-mannose
CAS: 74950-97-3
Ref. 3D-MC01852
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Product Information
2-Chloro-2-deoxy-D-mannose is a synthetic sugar that can be used as a fluoride substrate. It has been shown to bind to the active site of bacterial enzymes and inhibit them. 2-Chloro-2-deoxy-D-mannose is a conformationally constrained analogue of 3-deoxyglucose, which binds to the same active site on bacterial enzymes. This sugar also inhibits nitrate reductase, an enzyme involved in the reductive dehalogenation of nitrates. 2-Chloro-2-deoxy-D-mannose has been shown to inhibit the growth of Mycobacterium tuberculosis and Mycobacterium avium complex by binding with high affinity to the ligand binding site on these bacteria's glycolytic enzymes.
Chemical properties
Technical inquiry about: 3D-MC01852 2-Chloro-2-deoxy-D-mannose
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