Product Information
6-Chloro-6-deoxy-D-mannose is a naturally occurring sugar that is found in the spermatozoa of many animals. It is a mannose derivative that has been shown to be an inhibitor of the enzyme glyceraldehyde 3-phosphate dehydrogenase, which plays an important role in energy metabolism and isomerization of 6-phosphate to glucose-1 phosphate. This property may be responsible for its contraceptive effects. The drug also inhibits phosphoglucomutase and enhances the transfer of glucose from the liver to other tissues, increasing blood glucose concentrations. 6-Chloro-6 deoxy mannose also has antifertility effects in rats by inhibiting transfer of spermatozoa through the female reproductive tract.
Chemical properties
Technical inquiry about: 3D-MC08735 6-Chloro-6-deoxy-D-mannose
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