Ac-Lys-Thr-Lys-Gln-Leu-Arg-AMC
Ref. 3D-MCA-3185-V
| 5mg | 324.00 € |
Product Information
- Acetyl-L-Lysyl-L-Threonyl-L-Lysyl-L-Glutaminyl-L-Leucyl-L-Arginine 4-Methyl-Coumaryl-7-Amide Ac-Lys-Thr-Lys-Gln-Leu-Arg-MCA Ac-KTK LR-AMC
Ac-Lys-Thr-Lys-Gln-Leu-Arg-AMC is a peptide that is used as a research tool in the study of protein interactions. Ac-Lys-Thr-Lys-Gln-Leu-Arg-AMC binds to the acetylcholine receptor (AChR) at the interface between two subunits, which inhibits the formation of ion channels and blocks neurotransmission. This peptide has been shown to be a potent inhibitor of AChR activation by nicotinic agonists, such as acetylcholine (ACh), nicotine, and carbachol. Acetylcholine binding to AChRs induces conformational changes in the receptor that are transmitted across the synapse to activate postsynaptic receptors on muscle cells. Acetylcholine binding triggers an allosteric change in the AChR that results in increased permeability of ion channels, leading to depolarization of
Chemical properties
Technical inquiry about: 3D-MCA-3185-V Ac-Lys-Thr-Lys-Gln-Leu-Arg-AMC
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