2-Deoxy-D-ribonic acid-1,4-lactone

CAS: 34371-14-7

Ref. 3D-MD00127

Product Information

• Name: 2-Deoxy-D-ribonic acid-1,4-lactone
• Brand: Biosynth
• Description: 2-Deoxy-D-ribonic acid-1,4-lactone (2DRA) is a chemical compound with physiological effects. 2DRA is an irreversible inhibitor of DNA polymerase that has been shown to be a potent inhibitor of nuclear DNA synthesis in vitro and in vivo. The 2DRA inhibits the transfer reactions that are required for the replication of DNA. 2DRA binds to the nuclease domain of the enzyme and prevents it from cutting the phosphodiester bonds, leading to inhibition of DNA synthesis. This compound also has genotoxic effects and can cause mutation in cells through radiation or chemical treatment.

Chemical properties

• Molecular weight: 132.12 g/mol
• Formula: C₅H₈O₄
• Purity: Min. 95%
• Color/Form: Colorless Yellow Powder