Product Information
- 3-Dff
- D-Fructose, 3-deoxy-3-fluoro-
- (3S,4R,5R)-3-fluoro-1,4,5,6-tetrahydroxy-hexan-2-one
3-Deoxy-3-fluoro-D-fructose is a monosaccharide that has been used as an inhibitor of glucose uptake and metabolism in the lymphocytic leukemia cell line. This compound has been shown to inhibit the glucose transporter GLUT1, which is responsible for the transport of glucose across the plasma membrane. 3-Deoxy-3-fluoro-D-fructose inhibits cancer cells by inhibiting galactitol production through inhibition of gluconeogenesis. It also inhibits oxidative phosphorylation in lymphocytic leukemia cells, leading to apoptosis. 3-Deoxy-3-fluoro-D-fructose has been shown to inhibit cancer growth by blocking glucose uptake in xenopus oocytes.
Chemical properties
Technical inquiry about: 3D-MD03774 3-Deoxy-3-fluoro-D-fructose
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