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1-Deoxygalactonojirimycin hydrochloride salt
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1-Deoxygalactonojirimycin hydrochloride salt

CAS: 75172-81-5

Ref. 3D-MD06196

2mg
136.00 €
5mg
184.00 €
10mg
325.00 €
25mg
633.00 €
50mg
1,054.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024

Product Information

Name:
1-Deoxygalactonojirimycin hydrochloride salt
Synonyms:
  • (2R,3S,4R ,5S)-2-Methylolpiperidine-3,4,5-triol hydrochloride
  • 1-Deoxygalactonojirimycin hydrochloride
  • 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3S,4R,5S)-
  • 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride, (2R,3S,4R,5S)-
  • 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride, [2R-(2α,3α,4α,5β)]-
  • Galafold
  • Migalastat HCl
  • Migalastat hydrochloride
Description:

Specific and potent inhibitor of lysosomal α-galactosidase with IC50 in nanomolar range. It acts as pharmacological chaperone and assists folding of the wild type and mutant versions of the enzyme. It places itself in the instable active site and prevents the damage to the enzyme during the passage through Golgi apparatus, endoplasmatic reticulum and lysosome axis. The exposure to this compound leads to increased levels of functional α-galactosidase in models for lysosomal storage disorders and brings therapeutic benefits to patients with Fabry disease.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
199.63 g/mol
Formula:
C6H13NO4·HCl
Purity:
Min. 95 Area-%
Color/Form:
White Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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