Diacetone-D-glucose

CAS: 582-52-5

Ref. 3D-MD06795

Product Information

• Name: Diacetone-D-glucose
• Synonyms: 1,2:5,6-Di-O-isopropylidene-a-D-glucofuranoseDAG
• Brand: Biosynth
• Description: 1,2:5,6-Di-O-isopropylidene-alpha-D-glucofuranose, also known as diacetone-D-glucose (DAG), is a partially protected D-glucose sugar locked in the furanose form with isopropylidene protecting groups on the 1,2 and 5,6 positions. The unprotected 3 position is ready for a variety of chemical manipulations, such as alkylation, acylation or stereo-inversion. An orthogonal protecting group could be added to the 3 position to allow deprotection of an isopropylidene and therefore manipulations of the other hydroxyl groups. Diacetone-D-glucose has been used to make fluorinated hexopyranose glycolysis inhibitors useful in the treatment of brain tumours.

Chemical properties

• Molecular weight: 260.28 g/mol
• Formula: C₁₂H₂₀O₆
• Purity: Min. 98 Area-%
• Color/Form: White Off-White Powder