1,4:3,6-Dianhydro-D-glucitol

CAS: 652-67-5

Ref. 3D-MD07153

Product Information

• Name: 1,4:3,6-Dianhydro-D-glucitol
• Synonyms: 1,4,3,6-DianhydrosorbitolD-Isosorbide1,4:3,6-Dianhydro-D-sorbitol, (+)-<span class="text-smallcaps">D</span>-Isosorbide, 1,4:3,6-Dianhydro-<span class="text-smallcaps">D</span>-glucitol, 1,4:3,6-Dianhydro-<span class="text-smallcaps">D</span>-sorbitol, 1,4:3,6-Dianhydro-D-sorbitol, 1,4:3,6-Dianhydrosorbitol, 1,4:3,6-Dianhydrosorbitol 2,5-dinitrate, 1,4:3,6-dianhydro-D-altritol, 1,4:3,6-dianhydro-D-iditol, 1,4:3,6-dianhydro-L-glucitol, <span class="text-smallcaps">D</span>-Glucitol, 1,4:3,6-dianhydro-, Addolink 0312, At 101, Devicoran, Dianhydro-D-glucitol, Furo[3,2-b]furan, <span class="text-smallcaps">D</span>-glucitol deriv., Glucitol, 1,4:3,6-dianhydro-, <span class="text-smallcaps">D</span>-, Hydronol, Ismotic, Isobide, Isosorbitol, NSC 40725, Novasorb, Novosorb P, Polysorb, Polysorb B, Polysorb P, Polysorb PB, Polysorb PBA, Polysorb PS, Sorbitol, 1,4:3,6-dianhydro-

Description

Isosorbide dinitrate is a drug that belongs to the class of nitrates. It is used in the treatment of angina pectoris, as well as congestive heart failure and chronic heart failure. Isosorbide dinitrate has been shown to cause caspase-independent cell death in human leukemia cells and breast cancer cells. This may be due to its ability to inhibit mitochondrial membrane potential and interfere with intracellular calcium mobilization. The optimum concentration for isosorbide dinitrate is 10 µM, which inhibits the growth of bacteria, including Mycobacterium tuberculosis and Salmonella enterica serovar Typhimurium. The drug also inhibits the production of proinflammatory cytokines such as IL-1β, IL-6, and TNF-α by inhibiting c-jun phosphorylation. Isosorbide dinitrate also has anti-inflammatory properties, which may be due to its ability to inhibit 4-hyd

• Brand: Biosynth

Chemical properties

• Molecular weight: 146.14 g/mol
• Formula: C₆H₁₀O₄
• Purity: (%) Min. 98%
• Color/Form: White Off-White Powder