Thiamet G
CAS: 1009816-48-1
Ref. 3D-MD08856
| 25mg | 191.00 € | ||
| 50mg | 290.00 € | ||
| 100mg | 481.00 € | ||
| 250mg | 612.00 € | ||
| 500mg | 951.00 € |
Product Information
- 1,2-Dideoxy-2'-ethylamino-a-D-glucopyranoso-[2,1-d]-2'-thiazoline(3aR,5R,6S,7R,7aR)-2-(Ethylamino)-3 a,6,7,7a-tetrahydro-5-(hydroxy methyl)-5H-pyrano[3
- 2-d]thiazole-6,7-diol
Inhibits β-N-acetylglucosaminidase, also known as O-GlcNAcase (OGA), which cleaves the O-linked glycans from glycoproteins. Interferes with O-GlcNAc cycling and leads to the accumulation of O-GlcNAcylated proteins. Thiamet G elicits neuroprotective effects by modulating microglia/macrophages and inhibiting hyperphosphorylation of the microtubule-associated protein tau in models of stroke and Alzheimer’s disease. Thiamet G also has implications on diabetes and cardiovascular pathologies.
Chemical properties
Technical inquiry about: 3D-MD08856 Thiamet G
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