3-Deoxy-2-keto-D-gluconate lithium

CAS: 17510-99-5

Ref. 3D-MD165972

Product Information

• Name: 3-Deoxy-2-keto-D-gluconate lithium
• Synonyms: 2-Dehydro-3-deoxy-<span class="text-smallcaps">D</span>-gluconic acid, 2-Keto-3-Deoxy-<span class="text-smallcaps">D</span>-gluconic acid, 2-Keto-3-Deoxygluconate, 2-Keto-3-deoxy-D-gluconic acid, 2-Oxo-3-deoxy-<span class="text-smallcaps">D</span>-gluconate, 2-keto-3-Deoxy-<span class="text-smallcaps">D</span>-gluconate, 2-keto-3-Deoxygluconic acid, 3-Deoxy-2-oxo-<span class="text-smallcaps">D</span>-gluconate, 3-Deoxy-<span class="text-smallcaps">D</span>-erythro-2-hexulosonic acid, 3-Deoxy-<span class="text-smallcaps">D</span>-erythro-hex-2-ulosonic acid, 3-Deoxyhex-2-Ulosonic Acid, 3-deoxy-D-erythro-hex-2-ulosonic acid, <span class="text-smallcaps">D</span>-erythro-2-Hexulosonic acid, 3-deoxy-, <span class="text-smallcaps">D</span>-erythro-Hexulosonic acid, 3-deoxy-

Description

3-Deoxy-2-keto-D-gluconate lithium salt (3DG) is a molecule that is structurally similar to glucose. It has been shown to be an ATP-binding cassette transporter inhibitor, which prevents the transport of glucose by the glomerular filtration rate. 3DG is also an inhibitor of xylulose 5-phosphate reductase and fructose 1,6-bisphosphatase, leading to decreased synthesis of glycogen. 3DG can also inhibit gluconeogenesis in the liver by inhibiting phosphoenolpyruvate carboxykinase and pyruvate carboxylase activity. This molecule is chemically stable, meaning it will not break down into toxic substances when exposed to air or water. The enzyme activities of 3DG are being tested for their potential therapeutic effects in diabetes mellitus type 2 patients.

• Brand: Biosynth

Chemical properties

• Molecular weight: 178.14 g/mol
• Formula: C₆H₁₀O₆•Lix
• Purity: Min. 95%
• Color/Form: White Powder