1,4:3,6-Dianhydro-2-nitro-D-glucitol

CAS: 16106-20-0

Ref. 3D-MD24729

Product Information

• Name: 1,4:3,6-Dianhydro-2-nitro-D-glucitol
• Synonyms: Isosorbide 2-nitrate6-Nitrooxyhexahydro-furo[3,2-b]furan-3-ol1,4:3,6-Dianhydro-D-glucitol 2-mononitrate, 1,4:3,6-Dianhydro-<span class="text-smallcaps">D</span>-glucitol 2-mononitrate, 1,4:3,6-Dianhydro-<span class="text-smallcaps">D</span>-glucitol 2-nitrate, 1,4:3,6-Dianhydrosorbitol 2-mononitrate, 1,4:3,6-dianhydro-2-O-nitro-D-glucitol, 2-Ismn, <span class="text-smallcaps">D</span>-Glucitol, 1,4:3,6-dianhydro-, 2-nitrate, D-Glucitol, 1,4:3,6-dianhydro-, 2-nitrate (9CI), Furo[3,2-b]furan, <span class="text-smallcaps">D</span>-glucitol deriv., Glucitol, 1,4:3,6-dianhydro-, 2-nitrate, <span class="text-smallcaps">D</span>-, Glucitol, 1,4:3,6-dianhydro-, 2-nitrate, D-, Isosorbide 2-nitrate, Isosorbide-2-mononitrate

Description

Isosorbide is a dihydro-nitro sugar that belongs to the group of alkanoic acids. It is metabolized in the body by hydrolysis to yield two molecules of glucose and one molecule of nitrite ion. Isosorbide has been shown to have beneficial effects on chronic oral toxicity, systolic pressure, and myocardial infarct in experimental models. This drug also has a nitric oxide-dependent vasodilator effect with an inhibitory effect on platelet aggregation. Isosorbide has been shown to be effective against liver cells and is used as a diagnostic agent for liver diseases. In vivo human studies have demonstrated that this drug is absorbed quickly by the body and excreted primarily through the urine. This drug also exhibits pharmacokinetic properties that are dependent on pH levels for absorption.

• Brand: Biosynth

Chemical properties

• Molecular weight: 191.14 g/mol
• Formula: C₆H₉NO₆
• Purity: Min. 95%
• Color/Form: White Powder