Product Information
Name:1,4-Dideoxy-1,4-imino-D-arabinitol
Synonyms:
- DAB(2R
- 3R
- 4R) - 2- (Hydroxymethyl) - 3
- 4- pyrrolidinediol
Brand:Biosynth
Description:1,4-Dideoxy-1,4-imino-D-arabinitol (1,4DA) is an inhibitor of glycolysis that has potent inhibitory activity against the enzyme phosphofructokinase. It has been shown to decrease cellular ATP levels in rat liver and kidney tissues. 1,4DA also inhibits urine production by inhibiting the conversion of fructose to glucose in the kidney. This compound is a racemic mixture with two enantiomers: R and S. The pharmacokinetics of 1,4DA have been studied in rats and humans using a model system. In rats, 1,4DA was absorbed rapidly and excreted unchanged in the urine. In humans, this drug was well absorbed after oral administration and metabolized mainly by hydrolysis to form 1,4-dideoxyfructose (Fru).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:133.15 g/mol
Formula:C5H11NO3
Purity:Min. 95%
InChI:InChI=1S/C5H11NO3/c7-2-3-5(9)4(8)1-6-3/h3-9H,1-2H2
InChI key:InChIKey=OQEBIHBLFRADNM-UHFFFAOYSA-N
SMILES:OCC1NCC(O)C1O
Technical inquiry about: 1,4-Dideoxy-1,4-imino-D-arabinitol
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