3,4-Dideoxyglucosone-3-ene

CAS: 252006-38-5

Ref. 3D-MD44643

Product Information

• Name: 3,4-Dideoxyglucosone-3-ene
• Synonyms: 3,4-DGE, 3,4-dideoxyglucosone-3-ene, 2H-Pyran-3(6H)-one 2-hydroxy-6-(hydroxymethyl)-, (6r)-, 2H-Pyran-3(6H)-one, 2-hydroxy-6-(hydroxymethyl)-, (6R)-, (6R)-2-Hydroxy-6-(hydroxymethyl)-2H-pyran-3(6H)-one

Description

3,4-di-deoxyglucosone-3-ene is a bioreactive glucose degradation product which can be formed during heat sterilisation of glucose containing peritoneal dialysis solutions. Chemically, 3,4-Dideoxyglucosone-3-ene is an α,β-unsaturated carbonyl compound which increases its reactivity with cellular sulfhydryl, amino groups, proteins, and DNA. 3,4-Dideoxyglucosone-3-ene induces apoptosis in neutrophils, renal cells and peripheral blood mononuclear cells. Such induction leads to impaired peritoneal antibacterial defence.

• Brand: Biosynth

Chemical properties

• Molecular weight: 144.13 g/mol
• Formula: C₆H₈O₄
• Purity: Min. 95 Area-%
• Color/Form: Colorless Powder
• InChI: InChI=1S/C6H8O4/c7-3-4-1-2-5(8)6(9)10-4/h1-2,4,6-7,9H,3H2/t4-,6?/m1/s1
• InChI key: InChIKey=WNKYVCKDIDTELO-NJXYFUOMSA-N
• SMILES: O=C1C=C[C@H](CO)OC1O