Product Information
Name:Leptomycin A
Brand:Biosynth
Description:Leptomycin A is a Streptomyces-produced inhibitor, which is derived from the bacterium Streptomyces spiroverticillatus. It functions by specifically binding to and inhibiting the CRM1 (exportin 1), a nuclear export receptor. This action blocks the nuclear export of proteins that contain a leucine-rich nuclear export signal (NES), thereby leading to their accumulation within the nucleus. The inhibition of CRM1 disrupts various cellular processes, including cell cycle regulation and signal transduction pathways.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:526.7 g/mol
Formula:C32H46O6
Purity:Min. 95%
Technical inquiry about: Leptomycin A
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