Product Information
- (2S,3R,3aR)-2-(3,4-Dimethoxyphenyl)-3,3a-dihydro-3a-methoxy-3-methyl-5-(2-propen-1-yl)-6(2H)-benzofuranone
- 6(2H)-Benzofuranone, 2-(3,4-dimethoxyphenyl)-3,3a-dihydro-3a-methoxy-3-methyl-5-(2-propen-1-yl)-, (2S,3R,3aR)-
- 6(2H)-Benzofuranone, 2-(3,4-dimethoxyphenyl)-3,3a-dihydro-3a-methoxy-3-methyl-5-(2-propenyl)-, (2S,3R,3aR)-
- 6(2H)-Benzofuranone, 2-(3,4-dimethoxyphenyl)-3,3a-dihydro-3a-methoxy-3-methyl-5-(2-propenyl)-, [2S-(2α,3β,3aβ)]-
Denudatin B is a polycyclic diterpene that has been shown to have significant cytotoxicity against HL-60 cells. It also inhibits the activity of human polymorphonuclear leukocytes, which are white blood cells that play an important role in the body's immune response. Denudatin B has been shown to inhibit the activity of ATP-dependent drug efflux pumps such as P-glycoprotein (Pgp), which may be due to its ability to bind and inhibit these pumps. This compound has also been shown to induce apoptosis in vitro and in vivo. Denudatin B has antimicrobial effects, inhibiting bacterial growth by binding to DNA-dependent RNA polymerase
Chemical properties
Technical inquiry about: 3D-MDA40288 Denudatin B
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