Product Information
Name:Ethyl 2,3-O-isopropylidene-a-L-thiorhamnopyranoside
Brand:Biosynth
Description:Ethyl 2,3-O-isopropylidene-a-L-thiorhamnopyranoside (Ip) is a glycosylation inhibitor that inhibits the formation of an alpha-(1,2)-link between glucose and mannose in the glycosylation of the pentasaccharide. The maximum tolerated dosages of Ip have been determined in HL-60 cells. Trichloroacetimidate is used as a substitute for Ip in these experiments because it can be dissolved in water and has a high therapeutic index. Convergent synthesis of Ip was achieved by reacting pentasaccharides with trichloroacetimidate to produce pentasaccharides with substituted mannose residues at position two and three.
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Chemical properties
Molecular weight:248.34 g/mol
Formula:C11H20O4S
Purity:Min. 95%
Technical inquiry about: Ethyl 2,3-O-isopropylidene-a-L-thiorhamnopyranoside
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