L-Fucose

CAS: 2438-80-4

Ref. 3D-MF06710

Product Information

• Name: L-Fucose
• Synonyms: 6-Deoxy-L-galactose L-(-)-Rhodeose Fucose, (-)-Fucose, (-)-L-Fucose, 6-Deoxy-<span class="text-smallcaps">L</span>-galactose, 6-Deoxy-L-galactose, 6-Desoxy-L-β-galaktose, 6-Desoxygalactose, 6-deoxy-L-β-galactose, 6-desoxi-L-β-galactosa, 6-desoxy-L-β-galactose, <span class="text-smallcaps">L</span>-(-)-Fucose, <span class="text-smallcaps">L</span>-Galactomethylose, <span class="text-smallcaps">L</span>-Galactose, 6-deoxy-, Fucose, <span class="text-smallcaps">L</span>-, Fucose, L-, L-Galactomethylose

Description

Fucose (Fuc, 6-deoxy L-galactose) has a methyl group at C6 in place of a hydroxyl group and this gives the molecule a greater degree of hydrophobicity than galactose (Collins, 2006). L-fucose is found in fucoidan, a polysaccharide that occurs in the brown seaweeds (Phaeophyceae) (Percival, 1967). Fucose is also a key component in many mammalian N- and O-linked glycans, glycolipids, blood group substances and Lewis antigens (Becker, 2003). In human milk, neutral (fucosylated) oligosaccharides (HMO) contain fucose at the terminal position (e.g. 2’ -fucosyllactose and lactodifucopentaose). They represent 35% to 50% of the total HMO content and many in vitro studies suggest that HMOs directly modulate immune responses, acting either locally on cells of the mucosa-associated lymphoid tissues or systemically to inhibit the expression of inflammatory genes, mainly cytokines (Plaza-Diaz, 2018).

• Brand: Biosynth

Chemical properties

• Molecular weight: 164.16 g/mol
• Formula: C₆H₁₂O₅
• Purity: Min. 98 Area-%
• Color/Form: White Powder