L-Fucose

Ref. 3D-MF06710

Product Information

• Name: L-Fucose
• Synonyms: 6-Deoxy-L-galactose L-(-)-Rhodeose Fucose
• Brand: Biosynth
• Description: Fucose (Fuc, 6-deoxy L-galactose) has a methyl group at C6 in place of a hydroxyl group and this gives the molecule a greater degree of hydrophobicity than galactose (Collins, 2006). L-fucose is found in fucoidan, a polysaccharide that occurs in the brown seaweeds (Phaeophyceae) (Percival, 1967). Fucose is also a key component in many mammalian N- and O-linked glycans, glycolipids, blood group substances and Lewis antigens (Becker, 2003). In human milk, neutral (fucosylated) oligosaccharides (HMO) contain fucose at the terminal position (e.g. 2’ -fucosyllactose and lactodifucopentaose). They represent 35% to 50% of the total HMO content and many in vitro studies suggest that HMOs directly modulate immune responses, acting either locally on cells of the mucosa-associated lymphoid tissues or systemically to inhibit the expression of inflammatory genes, mainly cytokines (Plaza-Diaz, 2018).

Chemical properties

• Molecular weight: 164.16 g/mol
• Formula: C₆H₁₂O₅
• Purity: Min. 98 Area-%
• Color/Form: White Powder