Aptiganel
CAS: 137159-92-3
Ref. 3D-MFA15992
| 1mg | 924.00 € | ||
| 2mg | 1,276.00 € | ||
| 5mg | 2,319.00 € | ||
| 10mg | 3,478.00 € | ||
| 25mg | 4,058.00 € |
Product Information
- N-(3-Ethylphenyl)-N-methyl-N′-1-naphthalenylguanidine
- Guanidine, N-(3-ethylphenyl)-N-methyl-N′-1-naphthalenyl-
- 1-(3-Ethylphenyl)-1-methyl-2-naphthalen-1-ylguanidine
Aptiganel (CAS No. 137159-92-3) is a research tool that can be used to study the interaction of proteins and peptides with ion channels. It is an inhibitor of ion channels that blocks the flow of ions through them, thereby preventing the generation of action potentials. Aptiganel is a potent inhibitor of voltage-dependent calcium channels, which are found in neurons and muscle cells. This drug binds to ligands on the extracellular side of ion channel receptors and prevents ligand binding to the receptor, blocking ion flow. Aptiganel has been shown to inhibit voltage-gated potassium channels in rat dorsal root ganglion cells, human neuroblastoma cells grown in culture, and cultured mouse embryo spinal cord neurons. Aptiganel also inhibits voltage-gated sodium channels in rat dorsal root ganglion cells and cultured mouse embryo spinal cord neurons.
Chemical properties
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