PF 05241328
CAS: 1387633-03-5
Ref. 3D-MFC63303
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
- 1-[5-Chloro-6-(2-methylpropoxy)-3-pyridinyl]-3-methyl-N-(methylsulfonyl)-1H-indazole-5-carboxamide
PF 05241328 is a drug that binds to the voltage-gated sodium channel, which is responsible for the propagation of action potentials. It has been shown to have analgesic effects in animal models of chronic pain. PF 05241328 has a low affinity for other ion channels and receptors, which makes it a good candidate for use as a microdose. The drug's pharmacokinetics are noncompartmental, which means that all data can be used to calculate both the area under the curve and peak concentration values. This may lead to some outliers in the data set, but it allows for reproducible calculations without having to make any assumptions about the compartmental model.
PF 05241328's interaction with tissues such as hepatocytes is still unclear, but it is thought that this interaction may be due to its ability to inhibit signalling pathways related to inflammation and liver function.
Chemical properties
Technical inquiry about: 3D-MFC63303 PF 05241328
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