L-Glycero-D-manno-heptose
CAS: 4305-74-2
Ref. 3D-MG04722
| 1mg | 267.00 € | ||
| 2mg | 362.00 € | ||
| 5mg | 602.00 € | ||
| 10mg | 1,047.00 € | ||
| 25mg | 2,233.00 € |
Product Information
- glycero-manno-Heptose
- D-glycero-D-manno-Heptose
L-Glycero-D-manno-heptose is a polymyxin B antimicrobial agent that has been shown to have significant activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae. This compound also has an inhibitory effect on the growth of Gram-negative species such as Salmonella enterica. L-Glycero-D-manno-heptose inhibits the synthesis of bacterial cell wall peptidoglycan by binding to the terminal residues of oligosaccharides, which are linked to D-alanine in the peptidoglycan chain. The terminal residues of oligosaccharides are transferred from the lipid carrier to L-glycero-D manno heptose, forming a stable acylated glycoside. This reaction mechanism is similar to that of polymyxin B, but with a difference in reactivity due to steric hindrance.
Chemical properties
Technical inquiry about: 3D-MG04722 L-Glycero-D-manno-heptose
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