GDP-D-mannose disodium salt
CAS: 148296-46-2
Ref. 3D-MG05610
| 5mg | 208.00 € | ||
| 10mg | 263.00 € | ||
| 25mg | 459.00 € | ||
| 50mg | 812.00 € | ||
| 100mg | 1,189.00 € |
Product Information
- Guanosine 5'-diphospho-a-D-mannose disodium salt GDP-Man GDP-mannose
- guanosine 5′-diphospho-D-mannose disodium salt
GDP-D-mannose is a natural mannosyl donor and substrate for mannosyltransferases that catalyses mannosylation, for instance during the synthesis of the trimannoside core of complex, high-mannose or hybrid N-glycans. GDP-D-mannose is widely used in (chemo)enzymatic synthesis of oligosaccharides and its biosynthesis occurs from glucose-6-phosphate over several steps. GDP-D-mannose consists of a D-mannose unit, α-glycosydically linked to the nucleotide guanosine diphosphate (GDP). Examples of this important reaction would be the transfer of mannosyl moieties onto the dolichol-P-P-GlcNAc2 precursor of N-glycans in the endoplasmatic reticulum, with release of GDP, or the mannosylation reactions during GPI-anchor (bio)synthesis. GDP-D-mannose has also been used for the in vitro synthesis of b-mannan oligosaccharides.
Chemical properties
Technical inquiry about: 3D-MG05610 GDP-D-mannose disodium salt
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