Glycerone phosphate

CAS: 57-04-5

Ref. 3D-MG46658

Product Information

• Name: Glycerone phosphate
• Synonyms: (3-Hydroxy-2-oxopropoxy)phosphonic acid, 1,3-Dihydroxy-2-propanone phosphate, 1,3-Dihydroxyacetone 1-phosphate, 1-Hydroxy-2-Oxopropyl Phosphate, 1-Hydroxy-3-(phosphonooxy)-2-propanone, 1-Hydroxy-3-(phosphonooxy)aceton, 2-Propanone, 1,3-dihydroxy-, mono(dihydrogen phosphate), 2-Propanone, 1,3-dihydroxy-, phosphate, 2-Propanone, 1-hydroxy-3-(phosphonooxy)-, 3-(Fosfonooxi)-1-Hidroxiacetona, 3-Hydroxy-2-Oxopropyl Dihydrogen Phosphate, Dhap, Dihydroxyacetone 3-phosphate, Dihydroxyacetone monophosphate, Dihydroxyacetone phosphate, Dioxyacetone phosphate, Phosphodioxyacetone, Phosphoric acid, ester with 1,3-dihydroxy-2-propanone, 1-Hydroxy-3-(phosphonooxy)acetone

Description

Glycerone phosphate is a cytosolic calcium (Ca2+) substrate molecule that is used to measure the activity of phospholipase A2, an enzyme that catalyzes the hydrolysis of membrane lipids. Glycerone phosphate has been shown to inhibit neuronal death and may be useful in treating neurodegenerative diseases such as Alzheimer's disease. Glycerone phosphate has also been shown to bind to monoclonal antibodies, which are proteins that bind specifically to antigens on the surface of cancer cells, thereby preventing them from binding to their corresponding receptors on healthy cells. This may limit the spread of tumor growth and increase their sensitivity to platinum-based chemotherapy.

• Brand: Biosynth

Chemical properties

• Molecular weight: 170.06 g/mol
• Formula: C₃H₇O₆P
• Purity: Min. 95%
• InChI: InChI=1S/C3H7O6P/c4-1-3(5)2-9-10(6,7)8/h4H,1-2H2,(H2,6,7,8)
• InChI key: InChIKey=GNGACRATGGDKBX-UHFFFAOYSA-N
• SMILES: O=C(CO)COP(=O)(O)O