GDP-L-fucose disodium - low endotoxin grade
CAS: 148296-47-3
Ref. 3D-MG61412
1mg | 391.00 € | ||
2mg | 547.00 € | ||
5mg | 1,038.00 € | ||
10mg | 1,626.00 € | ||
25mg | 3,245.00 € |
Product Information
GDP-L-fucose is a natural fucosyl donor and substrate for fucosyltransferases (FUT) that catalyses the fucosylation of, for example, human milk oligosaccharides or glycoproteins. GDP-L-fucose is widely used in (chemo)enzymatic synthesis of glycans. Cymit Quimicaesis of GDP-L-fucose, a nucleotide sugar consisting of an L-fucose that is β-glycosidically linked to the nucleotide guanosine diphosphate (GDP), is achieved either through de novo synthesis via GDP-mannose or through a salvage pathway from free fucose. Fucosylation is catalysed by fucosyltransferases (~ 13 FUT genes have been identified in the human genome to date) to generate α-1,2, α-1,3, α-1-4 and α-1-6 linkages of fucose to other sugars, as well as direct linkages to peptides, with release of GDP (Lairson, 2008).
Chemical properties
Technical inquiry about: 3D-MG61412 GDP-L-fucose disodium - low endotoxin grade
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