N-Desmethyl (E)-α-hydroxy tamoxifen
CAS:
Ref. 3D-MGA07061
2mg
547.00€
5mg
978.00€
10mg
1,518.00€
25mg
2,904.00€
Product Information
Name:N-Desmethyl (E)-α-hydroxy tamoxifen
Brand:Biosynth
Description:N-Desmethyl (E)-α-hydroxy tamoxifen is a metabolite of tamoxifen. This drug has been shown to be more reactive than its parent compound, with the potential for enhanced toxicity. N-Desmethyl (E)-α-hydroxy tamoxifen is thought to be responsible for the toxic effects of tamoxifen in women and rats. The metabolites are excreted in the bile, with 50% being reabsorbed from the gastrointestinal tract and then excreted into the urine. In human liver cells, N-desmethyl (E)-α-hydroxy tamoxifen inhibits the growth of cancer cells and induces apoptosis by binding to DNA. It also causes increased production of reactive oxygen species in liver cells, which may contribute to hepatotoxicity.
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Chemical properties
Molecular weight:373.5 g/mol
Formula:C25H27NO2
Purity:Min. 95%
Technical inquiry about: N-Desmethyl (E)-α-hydroxy tamoxifen
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