4'-Hydroxypropranolol-4'-O-b-D-glucuronide

CAS: 94731-13-2

Ref. 3D-MH09957

Product Information

• Name: 4'-Hydroxypropranolol-4'-O-b-D-glucuronide
• Brand: Biosynth
• Description: Propranolol is a drug that belongs to the class of beta blockers, which are used to control high blood pressure in women and neonates. Propranolol is metabolized by glucuronidation and hydroxylation into 4'-hydroxypropranolol-4'-O-b-D-glucuronide. The hydroxy group on propranolol is metabolized by hydroxylation in the liver. This metabolic pathway leads to the formation of 4'-hydroxypropranolol-4'-O-b-D-glucuronide, which is excreted through urine samples and plasma concentrations. The hydroxy group on propranolol is also metabolized by glucuronidation, leading to the formation of low bioavailability of propranolol in humans. Propranolol has been shown to inhibit platelet aggregation at higher doses, but its effects on platelet aggregation are not predictable at lower doses.

Chemical properties

• Molecular weight: 451.47 g/mol
• Formula: C₂₂H₂₉NO₉
• Purity: Min. 95%