Haloperidol b-D-glucuronide

CAS: 100442-88-4

Ref. 3D-MH10160

Product Information

• Name: Haloperidol b-D-glucuronide
• Brand: Biosynth
• Description: Haloperidol b-D-glucuronide is the glucuronide conjugate of haloperidol. It is a major metabolite of haloperidol, which can be detected in urine samples and plasma concentration–time curves. It has been shown to be effective in the treatment of schizophrenic patients and is used as a marker for schizophrenia. Haloperidol b-D-glucuronide has been found to inhibit the reduction of carbonyl groups by human liver microsomes, but not rat liver microsomes. This inhibition may be due to its capacity to bind with human liver enzymes, such as cytochrome P450 reductase and glutathione reductase. Haloperidol b-D-glucuronide also inhibits the uptake of antipsychotic medications into human liver cells, but not rat liver cells.

Chemical properties

• Molecular weight: 551.99 g/mol
• Formula: C₂₇H₃₁ClFNO₈
• Purity: Min. 95%