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Z-VAD-FMK
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Z-VAD-FMK

CAS: 187389-52-2

Ref. 3D-MHA38952

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Estimated delivery in United States, on Monday 13 Jan 2025

Product Information

Name:
Z-VAD-FMK
Synonyms:
  • 13: PN: WO2005039629 PAGE: 18 claimed protein
  • 3: PN: WO2011028611 SEQID: 3 unclaimed protein
  • <span class="text-smallcaps">L</smallcap>-Alaninamide, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-
  • L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-
  • N-[(Benzyloxy)carbonyl]-L-valyl-N-[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]-L-alaninamide
  • N-[(Phenylmethoxy)Carbonyl]-L-Valyl-N-[(1S)-3-Fluoro-1-(2-Methoxy-2-Oxoethyl)-2-Oxopropyl]-L-Alaninamide
  • N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-<smallcap>L</span>-alaninamide
  • Z-VAD(OMe)-FMK
  • Z-Val-Ala-Asp(OMe)-FMK
  • z-VAD-FMK
  • See more synonyms
Description:

Z-VAD-FMK is a caspase inhibitor that blocks the activation of caspases. It inhibits IL-2 receptor and prevents apoptosis by blocking the nuclear DNA from entering the cell nucleus. Z-VAD-FMK has been shown to inhibit the death of HL60 cells in a model system. It has also been shown to have inhibitory properties against cyclin D2, which is an important factor in the apoptosis pathway. This drug may be used to treat conditions such as leukemia, psoriasis, and arthritis.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
467.49 g/mol
Formula:
C22H30FN3O7
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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