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Isofagomine D-tartrate
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Isofagomine D-tartrate

CAS: 957230-65-8

Ref. 3D-MI24675

1mg
273.00 €
2mg
400.00 €
5mg
711.00 €
10mg
1,021.00 €
25mg
2,041.00 €
Estimated delivery in United States, on Monday 28 Oct 2024

Product Information

Name:
Isofagomine D-tartrate
Synonyms:
  • (3R,4R,5R)-5-(Hydroxymethyl)-3,4-piperidinediol (2S,3S)-2,3-dihydroxybutanedioateAfegostat
Description:

Inhibitor of lysosomal acid β-glucosidase (GlcCerase/glucocerebrosidase) with IC50 in nanomolar range for wildtype and mutant enzyme. It behaves as pharmacological chaperon by binding to instable GlcCerase active site at neutral pH values and facilitating the protein folding. In acidic lysosomes, isofagomine gets release from the enzyme active site. This results in increased levels of functional glucocerebrosidase and brings therapeutic benefits to patients with Gaucher disease.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
297.26 g/mol
Formula:
C10H19NO9
Purity:
Min. 95%
Color/Form:
White Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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