Product Information
Name:Isofagomine hydrochloride
Synonyms:
- (3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diolAfegostat5-Hydroxymethyl-3,4-piperidinediol
Brand:Biosynth
Description:Inhibitor of lysosomal acid β-glucosidase (GlcCerase/glucocerebrosidase) with IC50 in nanomolar range for wildtype and mutant enzyme. It behaves as pharmacological chaperon by binding to instable GlcCerase active site at neutral pH values and facilitating the protein folding. In acidic lysosomes, isofagomine gets release from the enzyme active site. This results in increased levels of functional glucocerebrosidase and brings therapeutic benefits to patients with Gaucher disease.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:183.63 g/mol
Formula:C6H13NO3·HCl
Purity:Min. 95%
Color/Form:Powder
Technical inquiry about: Isofagomine hydrochloride
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