Sitagliptin monohydrochloride monohydrate

CAS: 862156-92-1

Ref. 3D-MJB15692

Product Information

• Name: Sitagliptin monohydrochloride monohydrate
• Brand: Biosynth
• Description: Sitagliptin monohydrochloride monohydrate is an inhibitor of dipeptidyl peptidase-4 (DPP-4), which is responsible for the degradation of incretin hormones. It is used in the treatment of type 2 diabetes mellitus, as it increases insulin secretion and reduces blood glucose levels. Recent studies have shown that Sitagliptin has anticancer properties, as it induces apoptosis in cancer cells. It also inhibits protein kinases, which are involved in tumor growth and metastasis. Capsaicin, a compound found in chili peppers, has been shown to enhance the anticancer activity of Sitagliptin in Chinese hamster ovary cells. The drug is excreted primarily through urine and has a low potential for drug interactions with other kinase inhibitors. Overall, Sitagliptin monohydrochloride monohydrate shows great promise as both a diabetes medication and an anticancer agent.

Chemical properties

• Molecular weight: 461.79 g/mol
• Formula: C₁₆H₁₈ClF₆N₅O₂
• Purity: Min. 95%
• Color/Form: Powder