Product Information
ZSET1446 is a zirconium oxide particle that contains dopamine. It is used for the treatment of neurodegenerative disorders, such as Parkinson's disease and schizophrenia. ZSET1446 has been shown to enhance the response of acetylcholine in mouse strains with a mutation in the α7 nicotinic acetylcholine receptor. This potentiation of cholinergic responses may be due to its ability to bind to dopamine receptors on the cell surface or its ability to act as an agonist at these receptors. ZSET1446 has also been shown to have psychotic effects, which may be due to its ability to bind to dopamine receptors on neurons. Chronic oral administration of this drug has been shown to result in potentiation of α7 nicotinic acetylcholine receptors and can lead to increased risk for psychosis.
Chemical properties
Technical inquiry about: 3D-MKB60394 ZSET1446
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