Product Information
MK-0674 is a synthetic compound with anti-tumor activity. It targets the tumor tissue by inhibiting the production of proteins that are vital for cell division. MK-0674 has been shown to be effective in animal studies and clinical trials, but it is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. MK-0674 has also been found to reduce the levels of collagen and nucleophilic carbonyls in cells exposed to oxidative stress, suggesting that it may have anti-oxidant properties. The drug is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid.
Chemical properties
Technical inquiry about: 3D-MKB78162 MK-0674
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