CAS 887781-62-6

Formula: C26H27F6N3O2

InChI: InChI=1S/C26H27F6N3O2/c1-24(2,29)13-19(23(37)35-25(14-33)11-12-25)34-21(26(30,31)32)18-9-5-16(6-10-18)15-3-7-17(8-4-15)20(36)22(27)28/h3-10,19-22,34,36H,11-13H2,1-2H3,(H,35,37)/t19-,20+,21-/m0/s1

InChI key: YTEORGORWDMMRK-HBMCJLEFSA-N

SMILES: CC(C)(C[C@@H](C(=O)NC1(CC1)C#N)N[C@@H](C2=CC=C(C=C2)C3=CC=C(C=C3)[C@H](C(F)F)O)C(F)(F)F)F

MK-0674

CAS: 887781-62-6

MK-0674

Formula: C₂₆H₂₇F₆N₃O₂

Purity: 99.5%

Molecular weight: 527.5

Ref: 54-BUP05451

MK-0674

CAS: 887781-62-6

Formula: C₂₆H₂₇F₆N₃O₂

Molecular weight: 527.5019

Ref: IN-DA01V4UP

MK-0674

CAS: 887781-62-6

MK-0674 is a synthetic compound with anti-tumor activity. It targets the tumor tissue by inhibiting the production of proteins that are vital for cell division. MK-0674 has been shown to be effective in animal studies and clinical trials, but it is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. MK-0674 has also been found to reduce the levels of collagen and nucleophilic carbonyls in cells exposed to oxidative stress, suggesting that it may have anti-oxidant properties. The drug is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid.

Formula: C₂₆H₂₇F₆N₃O₂

Purity: Min. 95%

Molecular weight: 527.5 g/mol

Ref: 3D-MKB78162

MK-0674

CAS: 887781-62-6

MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.

Formula: C₂₆H₂₇F₆N₃O₂

Purity: 99.59% - 99.99%

Color and Shape: White Solid

Molecular weight: 527.5

Ref: TM-T16089