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N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
CAS:
Ref. 3D-MLB56984
5mg
1,171.00€
10mg
1,628.00€
25mg
2,974.00€
50mg
4,757.00€
Product Information
Name:N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
Brand:Biosynth
Description:N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is a cytotoxic drug that belongs to the class of maytansinoids. It is metabolized in vivo to produce cytotoxic metabolites which inhibit protein synthesis by binding to ribosomes, preventing peptide bond formation. The preclinical studies have shown that N2'-deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine has a better therapeutic index than other maytansinoids, with fewer side effects. In animal models, N2'-deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine showed efficacy against human tumor cells and was not toxic to normal cells. This agent also showed no impurities when incubated with human liver microsomes and it was well tolerated in clinical trials in humans
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Chemical properties
Molecular weight:752.3 g/mol
Formula:C36H50ClN3O10S
Purity:Min. 95%
Technical inquiry about: N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
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