Propofol 2,3,4-tri-O-benzoyl-b-D-glucuronide methyl ester
Ref. 3D-MP07349
| 1mg | To inquire | ||
| 2mg | To inquire | ||
| 5mg | To inquire |
Product Information
Propofol is a general anesthetic that is used to induce and maintain anesthesia. It binds to GABA receptors in the brain, leading to suppression of neuronal activity. Propofol is metabolized by esterases in the liver, resulting in its active form 2,3,4-tri-O-benzoyl-b-D-glucuronide methyl ester. This active form inhibits glycolysis by inhibiting the conversion of glucose to fructose 1,6-bisphosphate and glyceraldehyde 3-phosphate by phosphoglucose isomerase and triose phosphate isomerase respectively. It also inhibits protein synthesis by binding to the ribosomes and preventing peptide bond formation on amino acids.
Propofol also has a number of other effects including inhibition of DNA synthesis by binding to DNA gyrase; inhibition of RNA synthesis by binding to RNA polymerase II; activation of K+ channels; and induction of apopt
Chemical properties
Technical inquiry about: 3D-MP07349 Propofol 2,3,4-tri-O-benzoyl-b-D-glucuronide methyl ester
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