Propylthiouracil N-b-D-glucuronide

CAS: 33987-24-5

Ref. 3D-MP16842

Product Information

• Name: Propylthiouracil N-b-D-glucuronide
• Synonyms: 1-Deoxy-1-(3,4-dihydro-4-oxo-6-propyl-2-thioxo-1(2H)-pyrimidinyl)- b-D-glucopyranuronic acid
• Brand: Biosynth
• Description: Propylthiouracil N-b-D-glucuronide is a glycosylation product of propylthiouracil, which is the active form of this drug. It has been shown to inhibit thyroid hormone synthesis by binding to the enzyme thyroid peroxidase. Propylthiouracil N-b-D-glucuronide is used in the treatment of thyrotoxicosis, and can also be used as an antithyroid agent for hyperthyroidism. It is chemically synthesized from propylthiouracil with a glycosyl group added at the C3 position on the thiourea ring by glycosyltransferases. This compound has also been fluorinated and polysaccharided, modified and saccharided, oligosaccharided or sugar, synthetic or monosaccharide, custom synthesis or high purity.

Chemical properties

• Molecular weight: 346.36 g/mol
• Formula: C₁₃H₁₈N₂O₇S
• Purity: Min. 95%