Polyphyllin A

CAS: 14144-06-0

Ref. 3D-MP42776

Product Information

• Name: Polyphyllin A
• Synonyms: TrillinCollettinside IFunkioside ADisoglusideMelongoside B, (25R)-spirost-5-en-3-yl beta-D-glucopyranoside, (3beta,25R)-spirost-5-en-3-yl beta-D-glucopyranoside, (3β,25R)-Spirost-5-en-3-yl β-<span class="text-smallcaps">D</span>-glucopyranoside, Alliumoside A, Collettiside I, Diosgenin 3-O-β-<span class="text-smallcaps">D</span>-glucopyranoside, Diosgenin 3-β-<span class="text-smallcaps">D</span>-glucoside, Diosgenin glucoside, Diosgenin β-<span class="text-smallcaps">D</span>-glucopyranoside, Diosgenin β-<span class="text-smallcaps">D</span>-glucoside, Diosgenin-B-D-blucoside, Funkioside A, Lilioglycoside A, Melongoside B, Polygonatoside A, Prosapogenin D′₃, Spiro[8H-naphth[2′,1′:4,5]indeno[2,1-b]furan-8,2′-[2H]pyran], β-<span class="text-smallcaps">D</span>-glucopyranoside deriv., Spirostan, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv., Trillin, β-<span class="text-smallcaps">D</span>-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl

Description

Polyphyllin A is a natural product that has been shown to have anti-oxidative effects. It has been demonstrated to inhibit the production of fatty acids by sephadex g-100, an enzyme activity by p. pastoris, and the production of antimicrobial peptides by tissue culture cells. Additionally, polyphyllin A has been shown to have anti-inflammatory properties and is used in traditional Chinese medicine for the treatment of cardiovascular diseases. Polyphyllin A also inhibits the oxidation of low density lipoprotein (LDL) cholesterol in coronary heart disease patients. Furthermore, polyphyllin A inhibits the proliferation of cancer cells such as leukemia HL-60 and K562 cells. The mechanism for this inhibition is not yet known but may be due to its ability to induce apoptosis or cause DNA damage.

• Brand: Biosynth

Chemical properties

• Molecular weight: 576.76 g/mol
• Formula: C₃₃H₅₂O₈
• Purity: Min. 95%