NAI 1

CAS: 1612756-29-2

Ref. 3D-MPC75629

Product Information

• Name: NAI 1
• Synonyms: [2-(azidomethyl)-3-pyridinyl]-1H-imidazol-1-yl-methanone
• Brand: Biosynth
• Description: NAI 1 is a peptidomimetic that has been shown to have neuroprotective effects in vitro. It also has an anti-depressant effect, and may be useful as a treatment for depression. NAI 1 is thought to work by binding to the melanocortin receptor and inhibiting the activity of tyrosine kinases, which are enzymes involved in the transmission of nerve impulses within the brain. NAI 1 has been shown to bind to aromatic hydrocarbons found in geochemical samples. These hydrocarbons are detectable at salinities up to 18%. The compound also inhibits bacterial growth, specifically by binding to the enzyme DNA gyrase, thereby preventing bacterial replication and transcription. NAI 1 binds with high affinity to a receptor found on many infectious bacteria, including Mycobacterium tuberculosis and Salmonella species. This activity is mediated through protein kinase C (PKC) activation and PKC-dependent tyrosine phosphorylation of cellular

Chemical properties

• Molecular weight: 228.21 g/mol
• Formula: C₁₀H₈N₆O
• Purity: Min. 95%
• Color/Form: Powder