Raltegravir b-D-glucuronide

CAS: 952654-62-5

Ref. 3D-MR09516

Product Information

• Name: Raltegravir b-D-glucuronide
• Brand: Biosynth
• Description: Raltegravir b-D-glucuronide is a synthetic, fluorinated analog of raltegravir. It is a potent HIV-1 integrase inhibitor that has been shown to be active against the majority of HIV-1 strains. Raltegravir b-D-glucuronide is less potent than the parent compound and exhibits reduced antiviral activity in vitro. Raltegravir b-D-glucuronide is metabolized to raltegravir and eliminated in urine as the glucuronide conjugate.

Chemical properties

• Molecular weight: 620.54 g/mol
• Formula: C₂₆H₂₉FN₆O₁₁
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C26H29FN6O11/c1-10-31-32-21(42-10)20(38)30-26(2,3)25-29-13(19(37)28-9-11-5-7-12(27)8-6-11)17(22(39)33(25)4)43-24-16(36)14(34)15(35)18(44-24)23(40)41/h5-8,14-16,18,24,34-36H,9H2,1-4H3,(H,28,37)(H,30,38)(H,40,41)/t14-,15-,16+,18-,24+/m0/s1
• InChI key: InChIKey=DNIJULFVNPGGMF-LKUMGPRMSA-N
• SMILES: Cc1nnc(C(=O)NC(C)(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O[C@@H]3O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]3O)c(=O)n2C)o1