Salicylic acid D-glucuronide
CAS: 7695-70-7
Ref. 3D-MS09950
| 1mg | 325.00 € | ||
| 2mg | 452.00 € | ||
| 5mg | 678.00 € | ||
| 10mg | 861.00 € | ||
| 25mg | 1,823.00 € |
Product Information
- 2-Carboxyphenyl b-D-glucopyranosiduronic acid
Salicylic acid D-glucuronide is the major metabolite of aspirin, which is formed by hydrolysis of acetylsalicylic acid. It has been demonstrated to have anti-inflammatory and analgesic effects. Salicylic acid D-glucuronide is excreted in urine and can be detected in human serum. The formation rate of this metabolite varies with the individual's age, sex, and kidney function.
Salicylic acid D-glucuronide can be formed in vitro using hydrochloric acid and acetylsalicylic acid as substrates. This reaction is catalyzed by the enzyme uridine diphosphate glucuronyltransferase (UGT). Salicylic acid D-glucuronide has been shown to form covalent adducts with hydroxyl groups from other molecules in vivo and in vitro, including proteins (e.g., albumin) and DNA bases (e.g.,
Chemical properties
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