Swainsonine
CAS: 72741-87-8
Ref. 3D-MS10129
1mg | 187.00 € | ||
5mg | 440.00 € | ||
10mg | 704.00 € | ||
25mg | 1,158.00 € | ||
2500µg | 351.00 € |
Product Information
- (1S,2R,8R,8αR)-1,2,3,5,6,7,8,8α-Octahydroindolizine-1,2,8-triolTridolgosir
- (1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol
- (1S,2R,8R,8aR)-octahydroindolizine-1,2,8-triol
- (8R,8aR)-octahydroindolizine-1,2,8-triol
- 1,2,8-Indolizinetriol, octahydro-, (1S,2R,8R,8aR)-
- 1,2,8-Indolizinetriol, octahydro-, [1S-(1α,2α,8β,8aβ)]-
- <span class="text-smallcaps">D</span>-Swainsonine
- Swainsonine From Rhizoctonia*Leguminicola
- Swainsonine Synthetic
- Swainsonine, Swainsona canescens
- See more synonyms
- Tridolgosir
Potent and specific inhibitor of α-mannosidase II with IC50 in submicromolar range. It inhibits three α-mannosidase II isoforms; MAN2A1 in Golgi apparatus, MAN2B1 in lysosomes and MAN2C1 in endoplasmatic reticulum. The compound reduces tumour growth and metastasis in mice by increasing the mannose content in N-linked glycans and directing the cell towards apoptosis.
Chemical properties
Technical inquiry about: 3D-MS10129 Swainsonine
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